BDBM395244 N-4-[rel-(5R,7S)-6,6-Dimethyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-5,7-methanoindol-2-yl]pyridin-2-ylcyclopropanecarboxamide::US10308629, Example 6

SMILES CC1(C)[C@@H]2C[C@H]1C(=O)c1c(Nc3ccccc3)c([nH]c21)-c1ccnc(NC(=O)C2CC2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395244   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395244(N-4-[rel-(5R,7S)-6,6-Dimethyl-4-oxo-3-(phenylamino...)
Affinity DataIC50:  63nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent